ea0016p66 | Bone and calcium | ECE2008
Scacchi Massimo
, Danesi Leila
, Cattaneo Agnese
, Valassi Elena
, Pecori Giraldi Francesca
, Argento Crocetta
, D'Angelo Emanuela
, Mirra Nadia
, Zanaboni Laura
, Tampieri Benedetta
, Cappellini Maria Domenica
, Cavagnini Francesco
GH and IGF-I exert an important role in the control of bone formation. Osteopenia and osteoporosis are a frequent recurrence in patients with thalassemia. Due to the high prevalence of GH deficiency (GHD) in adult thalassemic patients (Scacchi et al., Clin Endocrinol 2007), we investigated the possible role of GH - IGF-I abnormalities in the pathogenesis of the osteopenia/osteoporosis of this disease.Study: Sixty-four adult thalassemic pati...